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The secretion of IL-25 by tuft cells can also be modulated by the SCFA, succinate, produced by members of the intestinal microbiota, particularly species of the Bacteroidetes phylum who are prolific producers of this metabolite (Connors et al

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Cardiovascular outcomes data for Ozempic comes from the SELECT trial, which demonstrated a 20% reduction in major adverse cardiovascular events (heart attack, stroke, cardiovascular death) in patients with established heart disease but without diabetes

Important update: changes to PBS listing On 1 April 2024, a new PBS listing for empagliflozin was announced