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Mattson et al., 2008

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Nalidixic acid

It also improved the proliferative and secretory functions of fibroblasts and reversed morphological abnormalities of senescent cells (such as flattened cell shape, enlarged volume, and nuclear pyknosis)

Secondary endpoints showed improvements in waist circumference (13.5cm), HbA1c (0.45%), and cardiometabolic risk markers

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