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Over time, some people develop tolerance , meaning the same dose feels less effective

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Yau, K., Dharia, A., Alrowiyti, I

Gas and Bloating: The prolonged presence of food in the stomach can lead to increased fermentation by stomach bacteria, producing gas

Winfrey has said previously that she had an "aha" moment about using medication for weight loss after moderating a panel on weight for her Oprah Daily outlet last summer

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