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Novo Nordisk's semaglutide beats its counterpart liraglutide to become the next generation of weight loss innovation, and then Eli Lilly's GLP-1R/GIPR dual-target agonist tirzepatide achieves a 22.5% weight loss, surpassing semaglutide's weight loss history

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The hyperactivity ( GLP-1R knockout mice ( Similar to the alcohol-related responses, GLP-1R within the NTS, LDTg, VTA, and NAc modulates the behavioral responses induced by cocaine