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No Observed Effects On: Blood glucose or insulin sensitivity (no diabetogenic effects) IGF-1 levels (remained within normal ranges) Blood pressure or cardiovascular parameters Thyroid function Liver or kidney function markers Important: The absence of growth hormone-related side effects distinguishes AOD-9604 from full-length GH, which can cause fluid retention, joint pain, carpal tunnel syndrome, and insulin resistance

It means the evidence base is still developing

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In vivo OGP was found to regulate TGF-b1,b2,b3, FGF-2, IGF-I and aggrecan [85]

Studies by Hsieh and colleagues demonstrated that the peptide promotes VEGFR2 internalization through endocytosis, triggering downstream signaling cascades

The peptide works synergistically with caloric management and resistance training, potentially enhancing the results achievable through lifestyle modifications alone