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For both orally and parenterally administered NAC, nausea, vomiting and diarrhea have been reported, though rates of nausea and vomiting are higher with oral route [83]

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Variants in GLP1R, GIPR, FTO, and MC4R genes may provide context for underlying metabolic predispositions, helping providers understand whether an adolescent's weight concerns reflect genetic susceptibility to appetite regulation or energy storage patterns