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However, it is important to note that whilst these mechanisms are promising, the specific application to binge eating disorder requires careful clinical evaluation, as this condition involves complex psychological, behavioural, and biological factors that extend beyond appetite regulation alone

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In an animal high-altitude model, phosphorylated DSIP improved spatial-memory and sleep-architecture markers, but sample size was not clearly reported and this was not a healthy-human trial [11]

doi: 10.1210/edrv-16-3-390 16 MoodyAJThimLValverdeI

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Yadav SK, Singla-Pareek SL, Reddy MK, Sopory SK (2005) Transgenic tobacco plants overexpressing glyoxalase enzymes resist an increase in methylglyoxal and maintain higher reduced glutathione levels under salinity stress