In clinical trials, the most common observations were gastrointestinal effects: nausea (44.2% vs 17.4% placebo in STEP 1), diarrhea (30.0%), vomiting (24.8%), and constipation (24.2%)
Res Commun
Glycaemic outcomes were equally striking: 7782% of participants on retatrutide achieved euglycaemia (HbA1c 6.5%), and between 5763% achieved body weight reductions of 15% or more
95% CI, 0.36-0.61), ovarian cancer (HR = 0.52
Sean Scanlon, the Connecticut comptroller, said that not covering GLP-1s is shortsighted, bad policy. The state health plan, which takes care of teachers and other state employees, has been covering the drugs for weight loss since 2023
Benefits of Bariatric Surgery: Significant and sustained weight loss: Studies show bariatric surgery can lead to a weight loss of 30-50% of total body weight, with improved long-term weight management compared to medications alone