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According to the American Association of Clinical Endocrinologists and American College of Endocrinology (AACE/ACE) Obesity Clinical Practice Guidelines, weight loss medications should be considered as an adjunct to lifestyle therapy in all patients with T2DM as needed for weight loss sufficient to improve glycemic control, lipids, and blood pressure

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Examples of tricyclic antidepressants included but were not limited to amitriptyline and nortriptyline

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Preliminary studies indicate that stem cell therapy not only promotes angiogenesis but also reduces apoptosis, significantly improving sperm quality [352]