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There is no established evidence that allulose functions as a GLP-1 agonist in the pharmacological sense

doi: 10.1007/s00401-017-1731-9 160 LiCDengXXieXLiuYFriedmann AngeliJPLaiL

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Animal studies report biological activity after oral administration, especially in gastrointestinal models, which suggests potential local effectiveness

Studies report modulation of NO synthase activity and interaction with NO-mediated tissue protection pathways, which may underlie its broad cytoprotective profile

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