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( 5 Adrenal gland function Disturbances in the hypothalamus-pituitary-adrenal (HPA) axis, with an inadequate response during stressful conditions like infections or episodes of dehydration, have been suggested as potential causes of unexpected and unexplained deaths in PWS

The retina has enzymatic mechanisms for scavenging of free radicals as well as intrinsic antioxidant and redox systems for dealing with other types of ROS 17

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Among multiple safety parameters that have to be assessed, hemocompatibility is among the essential criteria