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In addition corticosteroids have been associated with local skin atrophy, depigmentation and muscle wasting, resulting in an increase in the bony prominence of the medial epicondyle

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As a result, the ETC functioning is disrupted, and ATP content becomes significantly depleted, which breaks down metabolic and ionic homeostasis and activates the degradative enzymes such as nucleases, proteases, and phospholipases [182, 188]

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