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These adverse effects are generally mild to moderate and improve over time, but they are the most frequent reason for treatment discontinuation

The results of this paper showed that mitochondrial dysfunction associated with cell apoptosis including membrane potential loss, down-regulation of Bcl-2 and up-regulation of Bax, activation of caspase-3, and the release of cytochrome c were abrogated in the presence of L-carnitine [52]

GLP-1 receptor agonists show no detrimental effect on sperm concentration and motility in vivo and in vitro

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