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The most common theory is that inflammation is the main cause of IC

Semaglutide was evaluated as monotherapy (PIONEER 1, 6 and 9), as an add-on to metformin (PIONEER 2), as an add-on to 1 to 2 oral antidiabetics (OADs) (PIONEER 3, 4, 10) or insulin with or without metformin (PIONEER 8)

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Mazziotti G, Frara S, Giustina A

This performance was driven by sustained demand for therapies targeting serious conditions, particularly Xolair (chronic hives, food allergies), Phesgo (breast cancer), Hemlibra (haemophilia A), Vabysmo (severe eye diseases), and Ocrevus (multiple sclerosis)

This is the single most common misclassification