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All 3 components of the primary outcome showed a trend for the benefit (including nonfatal strokes), although the individual effects did not reach significance

Mechanistic studies have revealed that Melanotan II's metabolic effects involve both central and peripheral melanocortin receptor populations

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Acetyl L-carnitine (ALC) is the derivative with increased neuronal bioavailability of L-carnitine , involved in the transport of long-chain fatty acids to the mitochondria the energy powerhouses of the cell

doi: 10.1186/s12931-022-02135-1 73

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