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2012), our observation that APAP decreased GJ abundance suggested that hepatocytes mount a defense against the spread of oxidative stress molecules within liver tissue during the early stages of APAP exposure by reducing the expression of Cx32 (and consequently GJs)

If a clot is pumped through the heart and into the body, it could reach the brain and cause a stroke

The half-life of a drug is the time it takes for the plasma concentration to reduce by half

2022 Apr 17;19(8):4870

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In late 2023, the FDA officially approved tirzepatide for chronic weight management under the new brand name Zepbound