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much lower at community doses Vomiting up to 36% at high doses Diarrhea 23-26% Constipation 17-19% Fatigue 11-13% Pancreatitis risk trials flagged severe abdominal pain for discontinuation and evaluation Gallbladder issues rapid weight loss increases gallstone risk Thyroid C-cell tumors same boxed warning as semaglutide (animal studies) GI side effects were more intense than semaglutide in trial data due to the dual mechanism
Support staff should gather histories and labs before the provider visit
c , Lysates from parental or Halo-RPB1 U2OS cells were analyzed by WB
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Riss, T., Niles, A., Moravec, R., Karassina, N