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Confirmed in the 2004 Phase 2 trial where fasting glucose remained unchanged after 12 weeks of daily dosing

[2] [11] As of 2026, retatrutide has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA), and it remains an experimental compound available only within authorised clinical trial settings

Anecdotal reports from research settings suggest mild stimulant-like effects in some individuals

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A: AOD-9604 includes an additional tyrosine (Tyr) residue at the N-terminus, making it technically Tyr-hGH Fragment 177-191