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As reported for Tanzeum 60 , the C-terminal L585 of the GLP-1 WT albiglutide-mimic and GLP-1 QMP fusions was removed upon exposure to CPA (Supplementary Table 2)

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Owing to the short plasma half-life of GLP1, several GLP1 receptor agonists (GLP1RAs) were developed with different chemical structures and pharmacokinetic profiles for type 2 diabetes mellitus (T2DM) treatment