Aronne has been part of multiple studies on GLP-1s, including the SURMOUNT-1 trial designed to see how well combining lifestyle changes and tirzepatide works in people on the verge of diabetes
Cell Metabolism, 27 (4), 740756
Stay Hydrated : Sip water throughout the day to avoid dehydration, especially if you experience nausea or diarrhea
Secondary Effects of GLP-1 Agonists: Acute GI Symptoms vs Chronic Gut Microbiome Dysbiosis Some secondary effects of GLP-1 RAs are symptomatic and relatively acute, such as gastrointestinal (GI) changes (constipation, diarrhea, nausea and vomiting), therefore mitigation strategies are well known
Wegovy is FDA approved to treat obesity
However, indirect effects of rapid weight lossincluding muscle loss, dehydration, and postural changescan trigger or worsen existing back pain in some patients