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PLoS ONE 8 , e55119 (2013)

Acute kidney injury manifests through creatinine elevation up to 110 mol/L versus the normal range of 45-90 mol/L

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Following these schedules as prescribed is essential for effective treatment

Pharmacological attempts to treat obesity have had limited success, with notable adverse effects, rendering bariatric surgery as the only current therapy for substantially improving body weight

Initial results from studies in rodents suggested a synergistic role of dual GLP-1 and glucagon agonism on reducing food intake and led to the development of numerous unimolecular GLP-1/glucagon co-agonists