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In TRIUMPH-4, it affected 8.8% of the 9mg group and 20.9% of the 12mg group, compared to just 0.7% on placebo

Associated with elevated NAD+ levels and SIRT1 activation in preclinical studies [2] [3]

24MechanickJI, YoudimA, JonesDB,

Timothy Brick, associate professor in Penn States College of Health and Human Development, and Jennifer Nyland, assistant professor in the department of neural and behavioral sciences at Penn State College of Medicine, will join the team as principal investigators

Additionally, retatrutide significantly improved blood lipids and blood pressure compared to placebo