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Ozempic (semaglutide for type 2 diabetes) uses a multi-dose pen requiring separate attachable pen needles (commonly 32G x 4 mm), unlike Wegovy's fixed needle system

AstraZeneca Key Development Products Elecoglipron Formerly AZD5004, ECC5004 Oral small-molecule GLP-1 receptor agonist Current Positioning AstraZeneca is developing elecoglipron, a candidate compound for which it acquired rights outside of China from the Chinese company Eccogene

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In Phase 2 trials published in The Lancet, patients on 0.5mg tesofensine lost an average of 11.3kg (about 10.6% body weight) over 24 weeksroughly double what was achieved with obesity medications available at that time

Achieving the right balance between GLP1R, GIPR and GR agonisation , would in principle be able to achieve even greater losses in weight, while still preserving lowering of blood glucose

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