week 1 tirzepatide What to Expect When Starting Tirzepatide: Complete Guide GLP1 week 3 update |

This was not a reported side effect in Wegovy clinical trials

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Overlap strategy (3 to 4 day gap): Administer final Wegovy dose on day 0

Tirzepatide is a once-weekly injection with a half-life of approximately 5 days, so the drug is always present in your system between doses

Liraglutide 3 mg (Saxenda, FDA-approved for weight management), an earlier-generation daily GLP-1 injection, demonstrates similar gastrointestinal side effect patterns with diarrhea reported in approximately 21% of patients according to its FDA label