For those prescribed Wegovy via the NHS, current NICE guidance (TA875) recommends a maximum of 2 years of treatment within a specialist weight management service
Symptoms include high blood pressure, increased heart rate, hyperthermia, agitation, and confusion, which are life-threatening
Key metrics include mtDNA copy number (reflecting depletion), mtDNA deletion frequency measured through long-fragment PCR or digital PCR, and levels of oxidized mtDNA bases like 8-oxo-dG (111, 120)
Which Has More Clinical Evidence: NAD+ or Peptide Therapy
This helps track how well the medication is working and manage any side effects
According to a study, vitamin B12 deficiency is common but is more significant on strict vegetarians or vegans, and more people today are reaching for supplementation