It is normally obtained from an animal-based diet (Wolffenbuttel et al., 2024)
Las tasas de discontinuacin del tratamiento debido a eventos adversos fueron del 8,7% y 9,7% con orforglipron 12 y 36 mg frente a 4,5% y 4,9% con semaglutida oral en ACHIEVE-3
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While initial safety concerns surrounding pancreatic and thyroid cancers led to regulatory scrutiny of incretin-based therapies, this meta-analysis of 93 RCTs shows no significant increase in pancreatic cancer risk