The current fervor for GLP-1RAs in the capital markets as well as in the general public, especially in terms of weight reduction, is probably going to result in overuse, said Chun-Su Yuan, MD, PhD, the Cyrus Tang Professor of Anesthesia and Critical Care at the University of Chicago
Yet not everyone reports the same experience
Where the change has been felt most acutely is in the case of Weight Watchers a global company founded in 1963 that made many millions by offering weight-loss and diet programmes
Retatrutide has a half-life of approximately 6 days, so a brief interruption does not eliminate all therapeutic effect
The practical takeaway is that even a temporary course of retatrutide provides metabolic value beyond the weight loss itself
Wegovy and Saxenda, both injectables, are the only GLP-1s FDA-approved for obesity