However, large-scale clinical trials in humans are limited, so current evidence is preliminary
Drugs like Ozempic may also be misused by individuals already struggling with an eating disorder to suppress their appetite, compensate for binge eating episodes or manage fear of weight gain
Taken together, preclinical models of PD demonstrate the promising neuroprotective potential for GLP-1 receptor agonists to reduce inflammation and -synuclein accumulation, whilst restoring mitochondrial function and motor deficits
The simplicity of peptide nasal sprays also enhance the convenience of research, as they can be easily incorporated into the daily lives of study participants
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J Biol Chem 280 , 3376633774, doi: 10.1074/jbc.M504604200 (2005)