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El efecto dermatolgico ms relevante en la investigacin es el oscurecimiento generalizado de la piel y, de forma especfica, la intensificacin y el cambio de aspecto de lunares, nevos y eflides (pecas), lo que obliga a vigilar cualquier lesin pigmentada

Glucagon-like peptide-1 (GLP-1) is a hormone that is naturally produced in the body and is essential for controlling blood sugar levels and losing weight

However, the majority of these treatments have a number of negative consequences that limit their long-term usage [33]

Longitudinal studies have shown elevated inflammatory markers as a predictor of increased incidence of mobility limitation [12] or the risk of muscle strength loss [13]

The decision framework is straightforward: Need to lose less than 10% of body weight

A pathologist assessed the Picrosirius red sections and provided a METAVIR score following a protocol blinded to genotype