According to the UK Summary of Product Characteristics (SmPC), the most frequently reported adverse reactions include: Nausea (very common, particularly at higher doses) Diarrhoea and vomiting (common to very common) Decreased appetite (very common) Constipation (common) Abdominal pain or discomfort (common) Dyspepsia (indigestion) (common) These gastrointestinal effects are typically most pronounced when initiating treatment or increasing the dose, and often diminish over time as the body adjusts to the medication
Interestingly, they found that BD patients had lower Mediterranean Diet adherence than controls, showing unhealthy dietary patterns (western-type, pro-healthy carbohydrates, unhealthy snacks, and meats and potatoes)
Helps catch dose drift
American Society for Clinical Investigation: 2350
Most patients experience a minor pinch, but there is not a lasting ache that is usually felt with a vaccine shot (which is injected deeper into the muscle)
Blood test markers to discuss with a clinician Marker CBC with differential Why it matters Screens anemia, infection patterns, and general blood-cell context before interpreting fatigue changes
