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Fresh tendon strains, recent ligament sprains, new muscle tears, and post-surgical healing typically respond well

and in humans, HPX recycling has been implicated from plasma heme clearance studies ( In cultured cells, hemeHPX binding and heme delivery initiate a cytoprotective program of events (Montecinos et al., 2019), including the induction of the heme degrading enzyme heme oxygenase (HMOX1)