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All health claims are based on published peer-reviewed research cited above
2d) and the largest increase in lean mass (Fig
GLP-1 agonists pass into breast milk at low levels, and infant safety data is lacking
Across the three pivotal trials, peak mean body-weight reductions rank retatrutide 12 mg at 24.2% (48 weeks, Phase 2), tirzepatide 15 mg at 22.5% (72 weeks, Phase 3), and semaglutide 2.4 mg at 14.9% (68 weeks, Phase 3) [1][2][5]
These drugs should be discontinued in patients planning pregnancy or if an unexpected pregnancy is confirmed
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