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Many now report unexpected vulvar and vaginal changes after starting treatment

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Ensuring you are well-hydrated and taking the supplement with food can speed up this adjustment period

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Additive effect on kidney outcomes including macroalbuminuria was also expected from AMPLITUDE-O substudy, however, additive effect of semaglutide and SGLT2i on the composite kidney outcomes without macroalbuminuria was not indicated in the FLOW substudy [50]

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