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There is no official recognition of berberine as an alternative or complementary therapy within NHS clinical practice

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Self-reported community sources describe nausea most severe within 1-3 hours of injection, fading by 6-8 hours

Goodrick JC, Xu M, Finnegan R, Schilling BM, Schiavi S, Hoppe H, Wan NC (2001) High-level expression and stabilization of recombinant human chitinase produced in a continuous constitutive Pichia pastoris expression system