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This shift is driven by increased glucose uptake, GLUT translocation, reduced levels of glycolytic intermediates to stimulate glycogen breakdown, and elevated AMP levels, which activate AMPK

Participants were of mean ( s.d.) age 48.313.2 years, height 1.720.09 m, weight 102.013.9 kg, body mass index 34.22.7 kg m 2 and fat mass 33.17.1%

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