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Bradycardia-induced heart failure with preserved ejection fraction successfully treated with empagliflozin and theophylline: a case report

In 2012, our group reported a novel (4 + 3) strategy for preparing cyclohepta[ b ]indoles in a single chemical transformation by means of a three-component annulation reaction beginning with an indole, a carbonyl, and a diene 2

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Certain conditions, like a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2, can make these medications unsuitable

GLP-1 agonists were initially approved for treating type 2 diabetes, with subsequent approvals for chronic weight management and reduction of the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 diabetes

They slow gastric emptying , reduce appetite signals in the brain, improve insulin sensitivity, and alter food reward pathways