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Glucagon-like peptide-2 regulates release of chylomicrons from the intestine

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Phase 3 results sometimes regress toward more conservative figures

At the same time, the findings for clinical studies were more mixed, and long-term trials showed the possibility of a lower dementia risk with these drugs, but shorter trials did not show consistent cognitive improvements

Direct stimulation of these receptors may contribute to nausea and emesis, particularly during the initial weeks of treatment or following dose escalation

These findings align with emerging research on GLP-1RAs as novel pharmacotherapies for AUD, a condition with limited effective treatments [33]