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In the subgroup of 12,387 lupus nephritis patients, GLP-1 RAs not only reduced the risk of kidney disease progression but also decreased overall mortality rates

Average weight loss in studies is helpful for understanding trends, but individuals vary

These effects are generally dose-dependent and tend to be most pronounced during dose escalation periods

Many patients benefit from the Precision Peptide Genetic Test after starting treatment

Beyond glycemic effects, GLP-1 receptor agonists slow gastric emptying, which prolongs the sensation of fullness after meals and contributes to reduced caloric intake

More recently, the SELECT trial showed that semaglutide 2.4 mg reduced major adverse cardiovascular events in adults with overweight or obesity without diabetes