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The peptide has also been investigated for its effects on metalloproteinase balance, simultaneously upregulating tissue-repair MMPs while modulating TIMP expression

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C., Cho, K

Moreover, other ACSL enzymes, such as -eleostearic acid, require ACSL1 to exhibit pro-ferroptosis activity (22), while monounsaturated fatty acids require ACSL3 to perform anti-ferroptosis activities (23)

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This was not observed following acute morphine administration and was specific for the locus coeruleus and for GRK2, as levels of the closely similar kinase GRK3 were not affected (Terwilliger et al., 1994)