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Overall, although the overall absolute risk increase is small (27 cases per 10,000 persons treated per year), clinical practitioners should nevertheless take into account the potential risk of gallbladder or biliary diseases associated with GLP-1RAs, especially when used at higher doses, for longer durations, and for weight loss, and in case the patient has a history of lithiasis [64]

Other Prescription Medications Several other prescription medications can also help with weight loss, but they work in different ways and have varying levels of effectiveness

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Supplementary Video 5 (download MOV Example of cells shedding from H2BGFP-expressing esophageal epithelioids (Methods) imaged by confocal live imaging

It activates receptors in the central nervous system, particularly MC3R and MC4R