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Its cognitive potential is inferred from TREK-1 knockout mouse phenotypes (enhanced memory) and from neurogenesis data rather than direct cognitive testing

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Some major exceptions may include how blood pressure and systemic effects vary depending on the route of administration

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Sun et al (98) demonstrated that intracellular lactate overload under prolonged ischemia inactivates the AMPK/NRF2/GPX4 protective axis, thereby promoting myocardial ferroptosis and exacerbating cardiac injury

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