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There are three main regulatory levels of ferroptosis: (1) Xc/GSH/GPX4, (2) NAD(P)H/FSP1/CoQ10, and (3) GCH1/BH4/DHFR

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The oxidation state of iron affects its absorption mechanism in the gastrointestinal tract

408 Within this complex interplay of diet, metabolism, and inflammation, IL-17 has been identified as a key player in metabolic dysregulation associated with HFD, where inhibiting IL-17A production or blocking its receptor can attenuate obesity by enhancing adipose tissue browning and energy dissipation