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Evaluation: Body fat (DXA scanning) Lean mass Insulin sensitivity Energy expenditure What they found: The combination showed an additive effect on fat reduction vs monotherapy AOD-9604 partially protected lean mass during GLP-1-induced weight reduction Increased energy expenditure in combination (~3 % vs GLP-1 alone) No new safety signals Why it matters: It validates the concept of combination , the idea that AOD-9604 may not work on its own, but can add value in combination with incretin agonists

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Int Arch Allergy Immunol 112 (2), 115124

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www.auanet.org/content/media/azoospermicmale2010.pdf

She also had a tiff with Bette Davis , as on an episode of Johnny Carson's talk show, Davis called Dunaway one of the worst people she's ever worked with