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Loss of maternally-provided APX-1 from the P2 blastomere causes an excess of pharyngeal cells that is evident in later-stage embryos [16], readily assayed by tbx-38p::mCherry-Histone expression [1820]

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Patients commonly experience weight loss of 10% or more over several months, with full effects often observed within 12 to 24 weeks

its -carboxyl groups conjugate a variety of compounds including metal cations [41]

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