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Read the Original Investigation Cardioprotective Glucose-Lowering Agents and Dementia Risk. Read the Original Investigation GLP-1RA and SGLT2i Medications for Type 2 Diabetes and Alzheimer Disease and Related Dementias. Read the accompanying Editorial GLP-1 Receptor AgonistsFrom Breakthroughs in Cardiometabolic Treatment to Emerging Neuroprotective Potential. | JAMA Neurology

1 Introduction to GLP-1 Glucagon-like peptide-1 (GLP-1) is a peptide hormone that is produced in the intestine and in multiple other sites that are known for their role in regulating glucose metabolism

Multiomics confirm mitochondrial adaptations in response to SHP2/MEK inhibition To investigate the underlying properties of the screening response of our cell lines, we performed metabolomic, proteomic, and transcriptomic analyses

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