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meningitidis activates both canonical and non-canonical pathways in the host, with predominance of the alternative caspase-3 mediated-GSDME activation in vitro in different cell lines (Tal et al., 2022) and of the GSDMD-dependent pathway in vivo in an intracisternal infected mouse model of meningitis (Pagliuca et al., 2024)

After ending her talk show after 25 years, she went on to found and build the Harpo Network, an even larger empire

The exclusive Asia-Pacific gathering where leaders in oligonucleotide, peptide, mRNA, and genome editing converge to share cutting-edge strategies across discovery, development, and CMC advancing next-generation therapeutics through collaborative innovation

Resistance training three to four days per week forms the foundation

Bioorganic & Medicinal Chemistry Letters

doi: 10.1016/j.immuni.2012.03.013 53 YamamotoMSatoSHemmiHHoshinoKKaishoTSanjoHet al