Complementary work on fibroblast-derived induced neurons (Int J Mol Sci, 2024, PMC11546785) shows that short peptides of the AEDG class can protect induced neurons from age-associated changes
Selenium is a mineral that acts as a necessary component for glutathione peroxidase, the enzyme that actually performs the antioxidant work
Nature medicine, 2017 doi: Roos, C
It also enhances mitophagy and mitochondrial repair by modulating key autophagy regulators such as PTEN-induced kinase 1 (PINK1) and BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3), and activating the Ca 2+ CAMKK2AMPK signaling pathway (30, 31)
Hepatocyte growth factor attenuates cerebral ischemia-induced increase in permeability of the blood-brain barrier and decreases in expression of tight junctional proteins in cerebral vessels
Conte center, MH-094268, NIH MH 084018, MH-105660, and MH-107730, as well as foundation supports from the Stanley and S/R to A.S.