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Consistent with this model, NRF2 activation promotes transcription of genes involved in redox homeostasis and glutathione biosynthesis, including Gclc and Gclm (41, 63)

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JAMA 325(14):14141425 Garvey WT, Batterham RL, Bhatta M et al (2022) Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial