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While CADTH noted that the recommended maintenance dose is 7 mg or 14 mg, Clinical experts consulted by CADTH stated that some patients may receive a dose of semaglutide somewhere between 7 mg and 14 mg, depending on their glycemic control and adverse events experienced

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Promega) (for AMYRs) or coelenterazine h (Nanolight Technologies, Pinetop, AZ) (for CTR) was then added to cells at a final concentration of 1:1000 or 5 M, respectively, and incubated for a further 1015 min