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This favorable preclinical safety profile has led investigators to advocate for the initiation of formal human trials [52, 83]

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PMID 9655824

Microscopic analysis was employed to assess histopathological changes, with damage graded according to a previously established system ( 2.4 FITC-dextran permeability assay At the last day of experiments, the fluorescein isothiocyanate (FITC)-labeled dextran solution was prepared using PBS